People with more muscle mass tend to suffer less brain ageing, scientists have found, highlighting a potential downside of using weight-loss drugs that lead to loss of brawn as well as fat.
While lower levels of fat deep in the abdomen also help to keep the brain youthful, maintaining muscle appears to be a crucial contributor to cerebral health, according to the research released on Monday.
The study, presented to the Radiological Society of North America annual meeting, comes as questions grow about the long-term impact of so-called GLP-1 medicines used to combat obesity, such as Ozempic, Wegovy and Mounjaro.
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