Claims including by President Donald Trump that the children of pregnant women who use paracetamol are at higher risk of developing autism is unsupported by the evidence, according to a comprehensive review of research to date.
The study published in the Lancet late on Friday found no clinically important increase in the likelihood of autism, ADHD or intellectual disabilities. The US leader and the health secretary Robert F Kennedy Jr had suggested that the drug can affect brain development.
The analysis of past work backs the advice of leading medical bodies that paracetamol is safe for use in pregnancy under existing guidelines. It warns that previous research papers alleging harms may be unreliable because they are prone to distortions.