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Genentech culls muscle-preserving drug in genetic diseases, raising questions about obesity trial

Roche’s subsidiary Genentech has called off the late-stage development of a muscle-building drug in two rare genetic conditions, spinal muscular atrophy (SMA) and facioscapulohumeral muscular dystrophy (FSHD).

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Roche’s subsidiary Genentech has called off the late-stage development of a muscle-building drug in two rare genetic conditions, spinal muscular atrophy (SMA) and facioscapulohumeral muscular dystrophy (FSHD).

The move raises questions about whether the drug, called emugrobart, can succeed in its other trials, which are testing its ability to preserve muscle when combined with obesity meds, and as a monotherapy in diabetes.

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