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Updated: Do Pfizer’s monthly GLP-1 data justify Metsera’s $10B price tag?

Pfizer said Tuesday that the monthly injection that was one of the cornerstones of its $10 billion buyout of Metsera allowed obesity patients to lose up to 10.5% of their weight, on a placebo-adjusted basis, after just over six months.

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Pfizer said Tuesday that the monthly injection that was one of the cornerstones of its $10 billion buyout of Metsera allowed obesity patients to lose up to 10.5% of their weight, on a placebo-adjusted basis, after just over six months.

Shareholders were unimpressed with the data, appearing to doubt whether the results were good enough to vindicate Pfizer’s acquisition of the obesity-focused biotech. Pfizer’s shares $PFE were down 3% in early trading, on the same day it reported its full-year 2025 earnings.

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