“It was goosebumps for me,” says Sikhulile Moyo, laboratory director at the Botswana-Harvard Aids Institute Partnership in Gaborone. On November 19, Moyo observed “certain patterns of mutations that we’ve never seen” in four samples among 95 Covid-positive swabs randomly selected for genome sequencing.
“We saw something very strange,” says Moyo. Puzzled by the set of mutations, he double and triple checked the tests for contamination and to ensure they had captured more than 95 per cent of the viral genetic code — the benchmark of a good sequence.
Scientists in South Africa and Hong Kong were puzzling over the same perplexing constellation of genetic changes detected in their labs — far more than in any previous variant of Sars-Cov-2.