Effective treatments for two cancers may be a step closer thanks to studies of their genetic blueprints. The results of analyses of pancreatic and brain tumours are reported in two papers published online on the 5 Sep by the journal Science. Glioblastoma multiforme, known in the UK as grade 4 astrocytoma, is the most aggressive form of brain cancer. A team at Johns Hopkins University in the US has sequenced 20,000 genes from 20 different GBM tumours. It found a mutation of a single gene – IDH1 – was most common in patients aged under 35 and in those with secondary tumours.
得益于对两种癌症基因蓝图的研究，人类找到有效治疗方案的努力可能会更进一步。9月5日，由《科学》(Science)杂志在互联网上发表的两篇论文记录了对胰腺肿瘤和脑肿瘤的分析结果。在英国被称为四级星形细胞瘤(Astrocytoma)的多形性胶质母细胞瘤（Glioblastoma Multiforme，简称GBM），是一种最恶性的脑癌。美国约翰•霍普金斯大学(Johns Hopkins University)的一个小组对20个不同GBM肿瘤中的2万个基因进行了测序。该小组发现，一种单基因突变——IDH1——在年龄在35岁以下的患者和患有转移性肿瘤的患者中最为常见的。