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Fight on for national champions

Pfizer has ignited a takeover battle for one of the biggest prizes in the global pharmaceuticals sector with its £60bn approach for rival AstraZeneca in a move that has raised political concerns on both sides of the Atlantic.

Shares in AstraZeneca jumped 15 per cent yesterday after Pfizer publicly urged the London-listed group to enter talks over what would be the biggest foreign takeover in UK history.

Downing Street gave a cautiously positive reaction to the US drugmaker’s plan, citing its intention to shift the merged group’s tax domicile to the UK if the deal was successful as proof of Britain’s attractiveness to

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