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Researchers led by Broad Institute gene editing star David Liu have come up with a new use for prime editing that can tackle a bucket of diseases with the same root cause, which they say opens up a more straightforward path to address dozens or even hundreds of genetic diseases.
The ambitious idea could, in theory, offer sweeping ways to treat genetic diseases like cystic fibrosis, Tay-Sachs, and many very rare diseases that shorten lives and that, if they have treatments at all, currently rely on complicated or costly therapies unique to each ailment.