The first evidence has emerged that clinical features of Alzheimer’s disease, the most common cause of dementia, can be transmitted between people.
John Collinge and colleagues at University College London found signs of developing Alzheimer’s pathology in the brains of people who died of Creutzfeldt–Jakob disease (CJD), acquired through contaminated growth hormone.
Although the circumstances of the transmission are exceptional, the study of eight CJD patients, reported on Wednesday in the journal Nature and at the British Science Festival in Bradford, raises concerns that Alzheimer’s may be transmissible through some medical or surgical procedures.
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