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New clinical trial data on the in vivo CAR-T therapy that AstraZeneca acquired last year suggest that while the experimental treatment can curb multiple myeloma in some patients, it may not be safer than the cell therapies engineered in a lab.
Compared to conventional CAR-T cell therapies, which have upended multiple myeloma treatment but are challenging to make and give, in vivo cell therapies are meant to be a simple infusion that instructs a patient’s own cells to fight disease.
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