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AstraZeneca’s in vivo CAR-T led to early responses, but one death in China trial

New clinical trial data on the in vivo CAR-T therapy that AstraZeneca acquired last year suggest that while the experimental treatment can curb multiple myeloma in some patients, it may not be safer than the cell therapies engineered in a lab.

This report was first published by Endpoints News. To see the original version, click here

New clinical trial data on the in vivo CAR-T therapy that AstraZeneca acquired last year suggest that while the experimental treatment can curb multiple myeloma in some patients, it may not be safer than the cell therapies engineered in a lab.

Compared to conventional CAR-T cell therapies, which have upended multiple myeloma treatment but are challenging to make and give, in vivo cell therapies are meant to be a simple infusion that instructs a patient’s own cells to fight disease.

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